Immunetolerance相关论文
目的:探讨囊泡胺转运蛋白1(VAT1)的表达与胶质母细胞瘤(GBM)免疫微环境的相关性。方法:回顾性分析中国脑胶质瘤基因图谱(CGGA)计划......
Chinese Medicine Syndrome Distribution of Chronic Hepatitis B Virus Carriers in Immunotolerant Phase
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Prostate cancer is the most common malignancy in the reproductive system of older males.Androgen deprivation therapy (AD......
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Objective:Hope to provide a new way to prolong the survival time of limb grafts. Methods:The recipients in experimental ......
Objective Pancreatic ductal adenocarcinoma(PDAC)is the fourth most common cause of death from cancer worldwide,with a po......
Objective Background: Immune tolerance is vital for the pathophysiology of classical Hodgkin lymphoma(CHL)and the crucia......
Echinococcosis is a zoonotic parasitic disease of human and mammalians caused mainly by the larval stages of Echinococcu......
Functional Restoration of HBsAg-specific B cells Associates HBsAg Seroconversion in Patients with Ch
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A retrospective study on the significance of liver biopsy and hepatitis B surface antigen in chronic
Objectives To investigate changes in the HBV replication level along with the natural course of chronic HBV infection an......
Natural killer(NK)cells accumulate at the maternal–foetal interface in large numbers,but their exact roles in successfu......
The isolated vascularized femur transplantation model is one of the commonly used vascularized bone marrow transplant mo......
Role of a Novel C-type Lectin-like Inhibitory Receptor KLRL1 in Immune Tolerance and its Related Mec
KLRL1,which belongs to the killer cell lectin-like receptors (KLR),is encoded by the NK gene complex (NKC).Our previous ......
An innovative vaccine composed of the BAFF protein containing a unnatural amino acid triggers the pr
B cell-activating factor(BAFF)plays a fundamental role in B lymphocyte survival and homeostasis,and aberrant BAFF signal......
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Immature CD4+ dendritic cells conditioned with donor kidney antigen prolong renal allograft survival
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肺癌是世界范围内首位恶性肿瘤死亡原因，也是目前肿瘤防治中面临最严重的挑战。肺癌肿瘤微环境(TME)中完全的免疫抑制状态是肺癌发......
目的分析免疫耐受期（IT）慢性乙型肝炎病毒（HBV）感染者的肝组织病理特征及临床意义。方法纳入2015年1月至2019年12月在中国科学院大学宁......
树突状细胞（DC）是一类专职抗原递呈细胞（APC），通过传导不同的调节信号调节T细胞应答或耐受。因此，DC很有可能成为免疫治疗的有力工具和靶......
Liver transplantation is an established therapy for end-stage liver diseases. Graft rejection occurs unless the recipien......
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The Effect of CD3-Specific Monoclonal Antibody on Treating Experimental Autoimmune Myasthenia Gravis
CD3-specific monoclonal antibody was the first one used for clinical practice in field of transplantation. Recently,rene......
The homeostasis of the immune system depends on the balance between the immune response to an invaded pathogen and the i......
While only a small percentage of the liver as dendritic cells, they play a major role in the regulation of liver immunit......
IL-10 Gene Modified Dendritic Cells Inhibit T Helper Type 1-Mediated Alloimmune Responses and Promot
Dendritic cells (DCs)have the potency to regulate the outcome of autoimmunity through the modulation of immune responses......
自身免疫性疾病是机体对自身抗原的免疫耐受机制破坏，导致一个或多个器官的免疫性损伤。目前，大多数自身免疫性疾病的治疗策略仍是长......
桥本甲状腺炎是一种器官特异性免疫疾病,属于自身免疫性甲状腺病的一种,其发病率逐年升高,是原发性甲状腺功能减退症的主要原因之......
早产儿是一类特殊的群体,与早产相关的严重神经、呼吸、消化系统疾病的致残/致死率居高不下.异基因细胞移植可能是上述疾病治疗和......
目的探讨肝移植术后完全停用免疫抑制剂儿童的临床特征，寻找可能与术后免疫耐受形成有关的因素。方法回顾性分析我院2008年7月至200......
Influence of intrauterine injection of rat fetal hepatocytes on rejection of rat liver transplantati
AIM: To investigate the influence of immune toleranceinduced by intrauterine exposure to fetal hepatocytes onliver trans......
Establishment of Nasal Tolerance to Heat Shock Protein-60 Alleviates Atherosclerosis by Inducing TGF
Mounting evidence supports that a newly identified regulatory T cell (Treg),CD4+LAP+ Treg,is associated with oral tolera......
目的 分析日本血吸虫尾蚴感染小鼠体内髓源抑制性细胞(myeloid-derived suppressor cells,MDSC)的富集情况,初步探索其在抗血吸虫......
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目的 探讨白细胞介素-2(IL-2)mRNA及IL-10 mRNA表达水平对大鼠肝移植耐受的影响.方法 将实验大鼠随机分3组:Ⅰ组为急性排斥组; Ⅱ......
探讨CD4+ CD25+调节性T细胞作为细胞疫苗抑制小鼠同种异体胰岛移植物排斥反应的作用,采用免疫磁珠分离技术分选CD4+ CD25+调节性T......
目的 分析不同临床乙型肝炎病毒(HBV)慢性感染者外周血中CD4+CD25high调节性T细胞(Treg)的水平及其与各种临床指标的关系.方法 采......
目前对于维生素A及其衍生物在免疫调节的相关作用的研究已经取得了较大的进展,然而其在过敏性疾病中的作用还未明确,给其应用前景......
BACKGROUND: Nerve allograft rejection is an unavoidable problem for nerve allografts. Traumatic peripheral nerve injurie......
Infusion of donor hepatic non-parenchymal cells prolongs survival of skin allografts in mice:role of
BACKGROUND:?In the mouse skin allograft model, speciifc immune tolerance to the donor was induced by injection of donor ......
目的探讨供者脾细胞对同种异体心脏移植免疫耐受的诱导效果 ,为抗排斥反应治疗提供依据。方法分别采用供者脾细胞 (SPC)和环磷酰胺......
目的：探讨Ｈ－２Ｋ＾ｈ基因转移诱导小鼠移植免疫耐受的可行性。方法：通过洋病毒载体介导的基因转移技术，将供体小鼠的Ｈ－２Ｋ＾ｈ基因导入到肥体小鼠（ＢＡＬＢ／ｃ）的造血细......
Tolerance induction in immunologically intact adult rats with allogeneic spleen cell transfusion fro
Objective: To investigate whether donor-specific tolerance can be induced in adult rats with intact immune system. Metho......
目的建立耐受性树突状细胞（DC）过继转移诱导肾移植免疫耐受的动物模型，以探讨肾移植后的免疫耐受情况。方法体外分离和纯化供体SD大鼠......
